There's something about dropping out of the work force that makes you feel like you have a hole in your contamination suit. Those that you talked to daily, had lunch with, or even cracked jokes with...all of a sudden don't have your email anymore. Even more, those that still have their suits intact, don't seem to want to 'fraternize' with the likes of us, for fear of contamination themselves.
That's how I felt more strongly the first time round. My sanity challenged, my energy depleted and my sense of profession tested. The second time round, you get a little better at putting on your reserve tool belt and patching what holes you can find. Everything else, intact suit or not, is still the same, a challenge.